Microbiology

Biofilm

생물막

Definition

A structured community of microorganisms attached to a surface and enclosed in a self-produced protective matrix.

Detailed Explanation

Biofilms are not merely cell aggregates — they are organized communities with internal communication via quorum sensing, structural channels for nutrient flow, and extreme antibiotic tolerance (up to 1,000 times greater than planktonic cells). Dental plaque is a familiar biofilm. Medical device-associated biofilm infections are notoriously difficult to treat. Biofilms on ship hulls and industrial pipes cause enormous economic losses through biofouling and corrosion.

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