Herpetology

Regeneration

재생

Definition

The ability of some amphibians, particularly salamanders, to regrow lost body parts such as limbs or tails.

Detailed Explanation

Salamander limb regeneration involves dedifferentiation — mature cells at the wound site revert to a progenitor state, form a blastema (proliferating cell mass), and redifferentiate into the correct tissue types. Unlike lizard tail regeneration (which replaces bone with cartilage), salamander limbs are regenerated with full anatomical fidelity. Understanding the molecular mechanisms of salamander regeneration is a major biomedical research goal, with implications for human tissue repair and regenerative medicine.

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