Human Microbiome Project
Microbiology & Virology
2012
Discoverers: NIH HMP Consortium
Overview
Comprehensive characterisation of the microbial communities inhabiting the human body, cataloguing over 10,000 species across body sites.
Significance
Revealed that the human body harbours trillions of microorganisms essential for health, fundamentally changing our concept of what it means to be human.
Methodology
16S rRNA gene sequencing and whole-genome shotgun metagenomics of samples from 242 healthy volunteers across 18 body habitats.
Impact
- Mapped human-associated microbial diversity
- Linked microbiome to health and disease
- Launched microbiome therapeutics