Nitrosotalea is a genus of ammonia-oxidizing archaea in the phylum Thaumarchaeota, distinguished by their ability to perform nitrification under acidic conditions where most other nitrifying microorganisms cannot survive. Species within this genus have been detected in acidic soils worldwide, suggesting a significant but underappreciated role in nitrogen cycling in low-pH habitats. The genus was established following the cultivation of the type species from agricultural soil.